Bought an 2006 S2R1000 with 35,000 kms, what was I thinking, I know...
I knew the owner and full service history. He used it for two trips to Laguna and back and also rode it daily. Then I put about 10,000 on before selling it so it had around 45,000kms at that point, surprised I was able to sell it.
However, the only issues I ran into were, worn out clutch plates, typical maintenance, easy to replace, and leaky exhaust gaskets.
There are more lemons when it comes to buying a used Ducati, but solid maintenance will prevent most major issues.
Those maintenance concerns unfortunately have follow Ducati into their new lineup, which are 10x more reliable than the older models, esp. the dreaded "valve adjustment".
Miss that bike