I don't believe in going too crazy with extended drain intervals. Internals remain protected well past normal intervals, yes. But even the best of the best filters out there will not trap 100% of contaminants. And that is what eats your seals. Trucks with blown rear mains at 100k are pretty common, and one thing they all have in common is that they've had 3 maybe 4 oil changes at that point. I can see where synthetic would have its benefits for higher revving vehicles and engines with tighter clearances, and even then I'd go 7500kms max between changes. But for trucks and vehicles that will never even see 5000 rpm I wouldn't waste my money on synthetic.
Common sense, reasonable intervals>brand/type/weight.