* Paul Allen, Microsoft co-founder[2]
* Nicolas Cage, American Actor. Owned two Enzos over different period of time, both have since been sold.
* Eric Clapton, guitarist, took delivery of the first Enzo imported to the UK. Parisian police also stopped Clapton when he was reportedly doing 145 mph on a highway in Paris while driving his Enzo.[2]
* Joe Cole, Football player for England and FA Premier League club Chelsea F.C.
* Sergei Fedorov, NHL player. s/n 130689 Now owned by LV Eric, Las Vegas NV.
* Torsten Frings, Owner of black Enzo, and German International soccer star.
* Tommy Hilfiger, clothing designer. Hilfiger is believed to have a partial stake in the Ferrari dealer in Montreal, Quebec, and thus, his car is registered in Canada. s/n 133026
* Nick Mason, Pink Floyd drummer. His example was featured and driven on the UK TV show Top Gear. s/n 137445
* Pope John Paul II was given the 400th Enzo model by the factory. He sold the car at a Ferrari auction in Maranello, where it was bought by Donald W. Wallace, whose first Enzo is the second Enzo to be involved in a crash.
* Zahir Rana, Owner of bright yellow Enzo, and ZR Auto in Calgary, AB, Canada.
* Teemu Selänne, NHL player.
* Rod Stewart, Rock Star. s/n 136497[2]
* Frank Warren, Boxing Promoter - Car recently written off in collision with bus
* Pharrell Williams, music producer (The Neptunes), singer/rapper, frontman of the band N*E*R*D. Co-founder of the music label Star Trak.