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Thread: Novel coronavirus (2019-nCoV/COVID-19)

  1. #7881
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    This article explains the phenomenon quite well:
    https://www.motherjones.com/politics...ght-crusaders/

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    Quote Originally Posted by Buster View Post
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    Honestly, if I didn't have kids, I'd find humanity's descent rather amusing and well deserved.
    'The world is a tragedy to those who feel, but a comedy to those who think.'

    Quote Originally Posted by jutes View Post
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    I saw a youtube vid where anyone who can bench/squat/dead 2 plates for reps is immune.
    squat/dead yes but not bench lol i got the vitamins, just need the hcq
    max_boost is a name known to all
    Quote Originally Posted by max_boost View Post
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    Or the max boost portfolio lol xqq/hmmj/arkk/xgro/strathmore/Chinese food lol
    Quote Originally Posted by The_Rural_Juror View Post
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    This is diversification in a nut shell. Equity, Fixed Income, Tech, Stoner, Real Estate, and Steady Income.

  3. #7883
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    Interesting take on lock downs - Someone else posted this channel a while back, seems semi-informative at least.

    https://www.youtube.com/watch?v=Cp0hiFVm1U8


    "1) Covid-19 is so infectious (R0 of 5+) that it will pretty much make its way through a population regardless of the efforts to avoid it

    2) But, it only severely affects a small percentage of those who get it

    3) And, more interesting, it's appearing that herd immunity happens quickly, at around 15%

    This leads to the conclusion that lockdowns may not be worth it. While they may slow the rate of infection spread somewhat, the economic damage they do can dwarf the benefits of that delay."

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    Those first two points have been known for months. I can't believe this has to be said again, this far in. Lockdown is to keep the hospitals from being overloaded by that "small percentage", not to stop it in its tracks.

    Also herd immunity only works if the virus doesn't mutate. Which it had at least once already.

  5. #7885
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    Quote Originally Posted by Tik-Tok View Post
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    Also herd immunity only works if the virus doesn't mutate. Which it had at least once already.
    I have brought this up before, but I still don't think any conclusion was reached, so since the anti-vaxxer subject has been coming up again, would this fact not also mean that a vaccination would be next to useless as well since the virus is mutating? I mean if you can just catch it again, will this not mean it won't be anything other than any other flu that just never actually goes away? It just goes up and down seasonally in infection rates like normal, no?
    Bob Blakeborough

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    Quote Originally Posted by tirebob View Post
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    I have brought this up before, but I still don't think any conclusion was reached, so since the anti-vaxxer subject has been coming up again, would this fact not also mean that a vaccination would be next to useless as well since the virus is mutating? I mean if you can just catch it again, will this not mean it won't be anything other than any other flu that just never actually goes away? It just goes up and down seasonally in infection rates like normal, no?
    Yep. Exactly what it means. Health authorities will eventually be guessing what strain is likely in the area, and giving that vaccination, just like the normal flu.

    However once the vaccine for this one is approved, it will be easier to find and approve the next one, etc.

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    Quote Originally Posted by tirebob View Post
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    I have brought this up before, but I still don't think any conclusion was reached, so since the anti-vaxxer subject has been coming up again, would this fact not also mean that a vaccination would be next to useless as well since the virus is mutating? I mean if you can just catch it again, will this not mean it won't be anything other than any other flu that just never actually goes away? It just goes up and down seasonally in infection rates like normal, no?
    There isn't good reason to believe the virus will behave like the flu

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    Quote Originally Posted by Buster View Post
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    There isn't good reason to believe the virus will behave like the flu
    Is there a good reason to believe it won't? I don't mean that to sound pissy or anything, but really, what flu doesn't behave like the flu?
    Bob Blakeborough

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    Quote Originally Posted by tirebob View Post
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    Is there a good reason to believe it won't? I don't mean that to sound pissy or anything, but really, what flu doesn't behave like the flu?
    Influenza is generally an exception, not the rule.

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    Quote Originally Posted by Buster View Post
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    There isn't good reason to believe the virus will behave like the flu
    Been wondering about this, but aside from sharing some of the base symptoms, is a Coronavirus actually similar to Influenza in any way?

    I know we keep calling it a “flu”, but does that classification have much basis in medical fact? Sure an influenza and Coronavirus are both viral infections, but is that where the similarities end?

    Anyone have some virology background on this?
    Originally posted by Thales of Miletus

    If you think I have been trying to present myself as intellectually superior, then you truly are a dimwit.
    Originally posted by Toma
    fact.

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    Quote Originally Posted by killramos View Post
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    Been wondering about this, but aside from sharing some of the base symptoms, is a Coronavirus actually similar to Influenza in any way?

    I know we keep calling it a “flu”, but does that classification have much basis in medical fact? Sure an influenza and Coronavirus are both viral infections, but is that where the similarities end?

    Anyone have some virology background on this?
    They are entirely different. The “flu” is actually short for influenza, a negative sense RNA virus with no genetic proofreading capability. This introduces a greater mathematical possibility for a transcription error during replication which leads to a higher rate of mutation. It’s genetic material is a mirror image of what the actual RNA strand needs to be to produce the active protein. So it first has to decode itself in reverse, which is prone to errors, then produce the new viral proteins, then make copies of itself, but in reverse, another step prone to error, before finally repackaging itself into virions.

    Coronaviruses are positive sense single strand RNA viruses that has about twice as much genetic material as Influenza. They have some proofreading capability and the positive sense strand reduces its rate of mutation. The RNA in coronavirus directly codes for a protein without having to decode itself.

    The way they enter the host is also different. Influenza has entirely different proteins on its surface than SARS-CoV2. I would say that other than being viruses, they are not at all alike.

    As an analogy, they are probably more different genetically than a human and an insect.

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    Cool, thanks for that, I feel like that’s an important distinction that more people should be informed about (aka we should stop comparing the disease to something nearly irrelevant).

    That’s probably the most interesting thing about COVID I have heard in months.
    Last edited by killramos; 08-04-2020 at 08:14 PM.
    Originally posted by Thales of Miletus

    If you think I have been trying to present myself as intellectually superior, then you truly are a dimwit.
    Originally posted by Toma
    fact.

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    I am going to go out on a limb and say that xrayvsn may be smarter than an E.I.T.
    SIDE TALLWALLS SAVE LIVES

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    Quote Originally Posted by The_Rural_Juror View Post
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    I am going to go out on a limb and say that xrayvsn may be smarter than an E.I.T.
    That’s not a high bar, he’s clearly at least as smart as a room full of EIT’s
    Last edited by killramos; 08-04-2020 at 08:18 PM.
    Originally posted by Thales of Miletus

    If you think I have been trying to present myself as intellectually superior, then you truly are a dimwit.
    Originally posted by Toma
    fact.

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    Quote Originally Posted by killramos View Post
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    Been wondering about this, but aside from sharing some of the base symptoms, is a Coronavirus actually similar to Influenza in any way?

    I know we keep calling it a “flu”, but does that classification have much basis in medical fact? Sure an influenza and Coronavirus are both viral infections, but is that where the similarities end?

    Anyone have some virology background on this?
    I'm no virologist, but the common cold is based on 2 different viruses, one being a coronavirus, so I would think it would behave similarly and mutate.

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    Fucking EIT's know more at that stage of life than any that follow.

  17. #7897
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    Quote Originally Posted by killramos View Post
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    Been wondering about this, but aside from sharing some of the base symptoms, is a Coronavirus actually similar to Influenza in any way?

    I know we keep calling it a “flu”, but does that classification have much basis in medical fact? Sure an influenza and Coronavirus are both viral infections, but is that where the similarities end?

    Anyone have some virology background on this?
    They're both RNA viruses and that's about it.

    influenza is a respiratory virus. sars-cov2 is a virus that seems to target the epithelial cells which sometimes results in respiratory symptoms.

    The current expectation is that the vaccine will be effective vis-a-vis stability, but unknown the duration or degree of protection at this point. I think we will need a 30-60 booster.

    Edit: xrayvsn has a more comprehensive answer!

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    Quote Originally Posted by The_Penguin View Post
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    I'm no virologist, but the common cold is based on 2 different viruses, one being a coronavirus, so I would think it would behave similarly and mutate.
    Looks like you are no EIT either.

    Edit: It just dawned on me that Buster may be a pharmacological pusher.
    Last edited by The_Rural_Juror; 08-04-2020 at 08:40 PM.
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  19. #7899
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    Quote Originally Posted by xrayvsn View Post
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    They are entirely different. The “flu” is actually short for influenza, a negative sense RNA virus with no genetic proofreading capability. This introduces a greater mathematical possibility for a transcription error during replication which leads to a higher rate of mutation. It’s genetic material is a mirror image of what the actual RNA strand needs to be to produce the active protein. So it first has to decode itself in reverse, which is prone to errors, then produce the new viral proteins, then make copies of itself, but in reverse, another step prone to error, before finally repackaging itself into virions.

    Coronaviruses are positive sense single strand RNA viruses that has about twice as much genetic material as Influenza. They have some proofreading capability and the positive sense strand reduces its rate of mutation. The RNA in coronavirus directly codes for a protein without having to decode itself.

    The way they enter the host is also different. Influenza has entirely different proteins on its surface than SARS-CoV2. I would say that other than being viruses, they are not at all alike.

    As an analogy, they are probably more different genetically than a human and an insect.
    Interesting... I spent the last hour looking up differences and saw a lot of what you are talking about. I need to spend more time mining into this!
    Bob Blakeborough

  20. #7900
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    I thought this was a decent article today.

    Scientists Uncover Biological Signatures of the Worst Covid-19 Cases https://nyti.ms/3frWSHS
    SIDE TALLWALLS SAVE LIVES

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