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    Default COVID-19 Science Thread

    Since the other main thread is giving me dick cancer and some form of AIDS at the same time, I thought a more science focused thread would actually be useful.

    My favorite source of information on recent COVID science developments is the MedCram youtube channel. It's simply awesome. MedCram is an e-learning site run by a couple of doctors that in normal times is designed to provide teaching to med students. So it doesn't offer much in the way of opinion-type stuff and it doesn't play to the lowest common denominator. At least some training in biochemistry is helpful.

    Today's was on the data associated with Vitamin D and ARIs and COVID.



    Yesterday's was also interesting talking about vaccines:



    Highly recommended. They were talking about covid being a blood/endothelial disease way before it became mainstream.

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    Thanks to you, I watch this religiously now.

    But man, some topics are dry AF for normies like me.

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    .
    Last edited by 01RedDX; 09-23-2020 at 04:24 PM.

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    Quote Originally Posted by 01RedDX View Post
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    I've noticed a steadily growing consensus in two areas, blood type and vitamin D deficiency, in determining both illness severity and vulnerability.

    So the two simple things people should be aware of (regardless of pandemic) are their blood type and the need to take vitamin D, I take 5,000 IU daily, even when I get some sun.
    How did you arrive at 5000? I know that you can take too much VitD, I just haven't done enough research to see what is considered the safe upper bound.

    It seems almost all of the paths to increased mortality lead back to oxidative stress and risk of clotting. Diabetes, obesity, blood type, and any number of internal components that form critical parts of the chain (ie NAC, VitD, etc).

    - - - Updated - - -

    Quote Originally Posted by Xtrema View Post
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    Thanks to you, I watch this religiously now.

    But man, some topics are dry AF for normies like me.
    haha, ya, it's not designed to grab you. But I'm nerdtastic, so I find almost all of them interesting.

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    That is 12.5 times the recommended daily dose of Vitamin D according to the Mayo Clinic, and above 4,000 IU you can get some pretty serious side effects such as kidney damage. I'd maybe check with your doctor before taking that much.

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    Quote Originally Posted by 01RedDX View Post
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    So the two simple things people should be aware of (regardless of pandemic) are their blood type and the need to take vitamin D, I take 5,000 IU daily, even when I get some sun.
    Woah, I thought 4000IU is max?

    I only take 1000IU supplement in winter. I take nothing in summer as I'm outside a lot more.

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    I've been taking a multi-vitamin, fish oils, 1000mg vitamin C, 5000IU of Vitamin D3 for like the past 10 years give or take lol It has been great cuz you rarely get sick and when you do everything is fairly mild. Doctors say I'm healthy and to keep doing what I am doing. I like to think so too, combine that with weights and sports but anyway, I can't sleep so FML lol

    Looks like I better cut back on my vitamin D as I don't want any serious side effects such as kidney damage

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    Quote Originally Posted by max_boost View Post
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    I've been taking a multi-vitamin, fish oils, 1000mg vitamin C, 5000IU of Vitamin D3 for like the past 10 years give or take lol It has been great cuz you rarely get sick and when you do everything is fairly mild. Doctors say I'm healthy and to keep doing what I am doing. I like to think so too, combine that with weights and sports but anyway, I can't sleep so FML lol

    Looks like I better cut back on my vitamin D as I don't want any serious side effects such as kidney damage
    What brand multi vitamins do you take?

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    Quote Originally Posted by tonytiger55 View Post
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    What brand multi vitamins do you take?
    for the longest time I was taking @89coupe recommended Usana https://askthescientists.com/qa/cellsentials/

    tbh I switched because yellow pee was annoying and then I met a friend who was one of those health/nutrition related ppl etc. and recommended this https://www.seroyal.com/phyto-greens-capsules.html

    I have been taking the phyto greens for almost 2 years now

    Now if there are any beyond experts here, feel free to analyze those two and tell me the diff cuz sometimes I just blindly trust ppl i.e. Strathmore lol

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    To add I also take ZMA at night time (Zinc magnesium aspartate) https://www.healthline.com/nutrition/zma#benefits

    Who knows if all this really works or not but it seems like it does so until the Doctor tells me differently, I don't plan to change anything. It has kept me in pretty good shape and I need to be cuz #nodaysoff life

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    Vaccine Tracker
    https://newsinteractives.cbc.ca/coro...accinetracker/


    Looks like Oxford is our best hope right now but Sinovac seems to be better for people with weakened immune system but less effective. Sounds like both can be out of stage 3 by fall/early winter.

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    These guys are really good as well.

    https://www.microbe.tv/twiv/

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    Quote Originally Posted by Buster View Post
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    How did you arrive at 5000? I know that you can take too much VitD, I just haven't done enough research to see what is considered the safe upper bound.

    It seems almost all of the paths to increased mortality lead back to oxidative stress and risk of clotting. Diabetes, obesity, blood type, and any number of internal components that form critical parts of the chain (ie NAC, VitD, etc).

    - - - Updated - - -



    haha, ya, it's not designed to grab you. But I'm nerdtastic, so I find almost all of them interesting.
    Some of the reading I've done is saying 8000iu VitD is max dose. Above that you risk all these bad side effects. However people have taken upwards of 10,000iu with no adverse effects. I just keep it at 4000iu for myself.

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    I take 3-4 pills of the Costco vitamin D tablets (1000 IU each) everyday during the winter.

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    Chalk me up in the too much vit D. But.. it wasn’t.

    I did 11,000IU daily for months. Working nights, and working with my doctor, that was my normal.

    We ran the specific blood work, the 25-hydroxy Vit D test (25-OH) three times.

    11,000 put me into the upper normal range. Doc was surprised, we both came away really satisfied and he was really pleased that he learned some “real field study” data.

    Is 11,000 right for you? Could be.

    I also don’t do 11,000 anymore, however I occasionally hyper dose it. Twice a week of 20,000 IU.

    D is pretty benign and you need A LOT to overdose.

    Cliffs - get tested and 25-OH is the test you need. Before being tested do a 6 week trial of 2000IU to gauge a baseline.
    "The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents... some day the piecing together of dissociated knowledge will open up such terrifying vistas of reality, and of our frightful position therein, that we shall either go mad from the revelation or flee from the light into the peace and safety of a new Dark Age."

    -H.P. Lovecraft

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    That’s a lot of vitamin D lol...

    I thought I was high by taking the few hundred units in a daily multi and an extra 1000 a day as per doctor recommendations.
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    Posting just so this shows up for me on the 'What's New'
    Cos...

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    Vitamin D is incredibly safe as long as you are well hydrated. I suspect the vast majority is just pissed out, but if you feel good with that dosage, go nuts.
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    Quote Originally Posted by ExtraSlow View Post
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    Vitamin D is incredibly safe as long as you are well hydrated. I suspect the vast majority is just pissed out, but if you feel good with that dosage, go nuts.
    Vitamin D isn't water soluble, so it isn't just pissed out.
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    Looks like Oxford is pushing for human challenge trials. I've been calling for this for months, but it looks like it might finally happen.

    https://www.theguardian.com/science/...hallenge-trial

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