Novel coronavirus (2019-nCoV/COVID-19)

[Buster]

This quickly becomes a definition problem (asymptomatic, presymptomatic, maybe even "sub-symptomatic").

At the very least, spread by people who either don't know they are sick, or don't think that their symptoms are Covid is a significant problem. It probably is our most significant problem in terms of spread.

This is why the single biggest policy thing we could do is have antigen based testing approved and implemented immediately. But we don't have that, because gov'ts are bad at things.

[jutes]

Soon people will just get fed up and stop being tested when they feel sick. There are enough out there to ignore every other public health guideline like masks, who's going to risk getting tested positive and risk their livelihood. How many people went to go tested for influenza or anything else when they were sick? Covid will eventually turn into that, people will stop giving a fuck. It's already happening with the threat of lockdown 2.0.

[Buster]

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Any way you want to slice it and dice it, with a sample size of almost 4.5 million people - having 140 (average age 60) mostly elderly people in a hospital at the moment and 14 deaths thus far in the 0-59 age category, in no way is a pandemic, except in the eyes who are selling you fear.

I think that you are more scared than you admit that you are wrong on this, and it is driving you to spend a lot of time convincing yourself that what you say is true.

[ExtraSlow]

I have said before, but for a single adult individual, there's little benefit to getting tested.

[Buster]

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I have said before, but for a single adult individual, there's little benefit to getting tested.

PCR testing of non-symptomatic people? You're right.

rapid antigen testing to screen for non-symptomatic shedders? It would be a covid combo breaker.

[rage2]

I just want some serology testing so I know if I'm wasting my time right now. I want my invisibility card.

[revelations]

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I think that you are more scared than you admit that you are wrong on this, and it is driving you to spend a lot of time convincing yourself that what you say is true.

What part of the stats as stated, are incorrect?

[ExtraSlow]

No, you misunderstand me, there's little benefit to a single selfish individual to getting tested, symptomatic or not, PCR or Antigen.

Now, in terms of saving society and ending this pandemic, yeah, more testing, particularly that rapid antigen testing.

[Xtrema]

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Soon people will just get fed up and stop being tested when they feel sick. There are enough out there to ignore every other public health guideline like masks, who's going to risk getting tested positive and risk their livelihood. How many people went to go tested for influenza or anything else when they were sick? Covid will eventually turn into that, people will stop giving a fuck. It's already happening with the threat of lockdown 2.0.

You basically describe what's already happening. It's a self fulfilling prophecy.

They ask you to do whatever to stop the spread, nobody cares until it get bad enough in need of a full lockdown. Then they bitches about a full lockdown.

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I just want some serology testing so I know if I'm wasting my time right now. I want my invisibility card.

Well Japan tested 50% with antibody in July for people without symptoms. I wish we will do similar study here to see if 4 months of mask wearing has bought us the same thing.

The only study left to debate on is whether active antibodies are need to fight COVID. Some say once you got antibody, even after antibody leaves in 10-12 weeks, 2nd COVID infection won't be as severe or deadly as the body remembers how to fight it. Given we have such low death rate on the 2nd wave, there may be some evidence to support that.

[Tik-Tok]

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I just want some serology testing so I know if I'm wasting my time right now. I want my invisibility card.

$80 at Ichor.

Results won't make you invisible though.

https://ichorblood.ca/pages/COVID-19...ody+Testing/14

[tirebob]

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You basically describe what's already happening. It's a self fulfilling prophecy.

They ask you to do whatever to stop the spread, nobody cares until it get bad enough in need of a full lockdown. Then they bitches about a full lockdown.

I think most of those people are happy to just let it play out naturally and aren't concerned with stopping the spread. It has nothing to do with bad enough to require a lock down or not bad enough.

[Xtrema]

EU is f'd....

https://www.dw.com/en/coronavirus-be...oar/a-55459225

Belgium will run out of hospital beds in little over a week

https://www.washingtonpost.com/world...38b_story.html

For Germany, the breaking point could come in December. France and Switzerland might crack by mid-November. Belgium could hit its limit by the end of the week.

[Buster]

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No, you misunderstand me, there's little benefit to a single selfish individual to getting tested, symptomatic or not, PCR or Antigen.

Now, in terms of saving society and ending this pandemic, yeah, more testing, particularly that rapid antigen testing.

One development worth noting is that the treatment methodologies for covid are quite distinct from those in other diseases. In some cases different enough that drugs are used in a way that might be contra-indicated in other diseases. They have covid broken down into 3 phases, which all have really important implications for treatment. They consider it pre-infection (ie prevention). Then they consider it the "viral phase" which can be aided by anti-virals and other medications. There there is the "post viral" cytokine storm/inflammatory phase, which requires a switch from anti-virals to deal with - but not too see as some of the anti-inflammatory drugs might not be good for the viral phase.

On other words: PCR as a diagnostic test for symptomatic cases is becoming very important for proper treatment.

[Buster]

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The only study left to debate on is whether active antibodies are need to fight COVID. Some say once you got antibody, even after antibody leaves in 10-12 weeks, 2nd COVID infection won't be as severe or deadly as the body remembers how to fight it. Given we have such low death rate on the 2nd wave, there may be some evidence to support that.

Every TWiV is worth listening to in its entirety. However, this one is very recent and is mostly focused on the antibody discussion. Very much worth a listen.

[killramos]

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Every TWiV is worth listening to in its entirety. However, this one is very recent and is mostly focused on the antibody discussion. Very much worth a listen.

Did you watch this stuff before covid or has it been a long term interest for you?

[Buster]

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Did you watch this stuff before covid or has it been a long term interest for you?

My undergrad is in molecular biology/ biotechnology, and I was heading into PhD-land before I decided that postdoc and then grant-writing weren't my kettle of fish. I had a couple of my class mates go on to become prominent scientists in immunology and other related fields.

I didn't keep up on the technical side of things, so had to play some catch-up over the winter, but I did keep a passing interest in developments over the years and as I tracked some friends' careers. So I have some pros to ask questions directly, which helps. I didn't start listening to TWiV again religiously until recently.

[killramos]

Ha. Cool.

[vengie]

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My undergrad is in molecular biology/ biotechnology, and I was heading into PhD-land before I decided that postdoc and then grant-writing weren't my kettle of fish. I had a couple of my class mates go on to become prominent scientists in immunology and other related fields.

I didn't keep up on the technical side of things, so had to play some catch-up over the winter, but I did keep a passing interest in developments over the years and as I tracked some friends' careers. So I have some pros to ask questions directly, which helps. I didn't start listening to TWiV again religiously until recently.

You went from this into finance??
Wild

[Buster]

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You went from this into finance??
Wild

[nzwasp]

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EU is f'd....

https://www.dw.com/en/coronavirus-be...oar/a-55459225



https://www.washingtonpost.com/world...38b_story.html

How come they are seeing their beds fill up but the states and canada are not (well aside from manitoba)